coca

[Lrus007]

So the leaves are useful from the start? Does potency stay consistent throughout the life of the plant? Thanks for the info. Love this site. Peace GS
yes

impressive, do they need a lot of care?
no there tuff as hell set in glass of water to root takes about a month.

And generally...the suggestion that it needs to be grown at high altitude just means that a little more UV will help the Alkaloids develop. At least that seems like what I have read... H
yes higher altitude makes leafs stronger.

Lrus...what are the ones with the larger longer leaves? I only recognize the smaller leaves as coca. Looks like a rubber tree? H
that is older leaf's all coca plants in photo. they drip a white latex tho
never lick the white latex... it will burn the shit out of mouth you must
dry the leafs.

[Harvester]

Wow...Thanks for starting this.

I think this is cool just because it sould sit right in the window with the rest of the plants and no-one around here would know any different. It's look nice next to my 5ft San Pedro... ;)

I wonder if even the average LEO would recognize it...

Do they flower and go to seed? I know the seeds are only good for a week or so.

H

[Lrus007]

mine has never flowered here's more info
http://cocaine.org/cokleaf.html

[Harvester]

Read just enough to wonder...

Did we just find the best spider mite weapon ever? That white latex...

Not that we'd ever get enough or want to use it that way, just interesting reading about the evolutionary development of the alkaloids...

H

[Lrus007]

well the coca plants got big and out of hand.
so last night i took starts off them and stripped
the leafs off the plant's. so here there drying.

[spaceman]

all you need a is a gourd some sea shells, and a fancy bag.....wicked!

[Lrus007]

:yeahthat:

[Bohempian]

Sweet!
I just have small 7 seedlings of e.novogranatense and faster one's already have couple leaves :)
thanks for sharing!
btw. how big pots you use for old plants???

[spaceman]

http://phys.org/news/2012-06-cocaine.html

How plants make cocaine June 6, 2012 How plants make cocaine Enlarge This is the coca plant (Erythroxylum coca) and the molecular structure of cocaine (grey: carbon, blue: nitrogen, red: oxygen, white: hydrogen). Credit: Max Planck Institute for Chemical Ecology/ D’Auria, Jirschitzka Cocaine is one of the most commonly used (and abused) drugs, but we have almost no modern information on how plants produce this complex alkaloid. Researchers from the Max Planck Institute for Chemical Ecology in Jena, Germany, have just discovered a key reaction in cocaine formation in the coca plant from South America, and identified the responsible enzyme. This enzyme belongs to the aldo-keto-reductase protein family revealing new insights into the evolution of cocaine biosynthesis. Humans encounter alkaloids every day Alkaloids constitute a very large group of natural nitrogen-containing compounds with diverse effects on the human organism. A large variety of plant-produced alkaloids have strong pharmacological effects, and are used as toxins, stimulants, pharmaceuticals or recreational drugs, including caffeine, nicotine, morphine, quinine, strychnine, atropine and cocaine. Atropine, used to dilate the pupils of the eye, and the addictive drug cocaine are both tropane alkaloids which possess two distinctive, inter-connecting five- and seven-membered rings. Plants commonly produce tropane and other alkaloids for protection against herbivores and other enemies. Species in seven plant families are known to produce tropane alkaloids, including the Brassicaceae (mustard family), Solanaceae (nightshade or potato family) and Erythroxylaceae (coca family). These families are not closely related to each other. For example, it is assumed that the last common ancestor of the Erythroxylaceae and the Solanaceae lived about 120 million years ago. But how similar are the tropane alkaloid biosynthetic pathways in these families? Was there a single original tropane alkaloid pathway which was lost in most other plant families during the course of evolution? Or, did tropane alkaloid biosynthesis arise independently on several different occasions? How plants make cocaine Enlarge This image shows immunolabeling (green areas) of MecgoR, the enzyme catalyzing the penultimate step of cocaine biosynthesis. The picture shows the strong accumulation of the enzyme in a cross section of a very young E. coca leaf, which is still curled around the growing stem tip. Bar: 0,1 mm. Credit: Max Planck Institute for Chemical Ecology/ D’Auria, Jirschitzka Atropine and cocaine: Two tropane alkaloids, two plant species, two different enzymes John D'Auria, project leader in the Department of Biochemistry at the Max Planck Institute for Chemical Ecology, has been studying the coca plant, from which the drug cocaine is derived. Native tribes in South America have been cultivating coca and chewing its leaves for at least 8000 years for their stimulant and hunger-suppressing properties. Although the formation of cocaine has not been investigated in the last 40 years, the biosynthesis of the related tropane alkaloid, atropine, from belladonna (Solanaceae) is well-established. In the penultimate step, a ketone function is reduced to an alcohol residue. This key reaction is catalyzed by an enzyme of the short-chain dehydrogenase/reductase (SDR) protein family in belladonna. Among this group of enzymes are also many alcohol-degrading dehydrogenases in animals. To find the corresponding enzyme in cocaine biosynthesis, Jan Jirschitzka, a PhD student in the group, searched the genome of the coca plant to look for SDR-like proteins. However, all the SDR genes that he cloned and expressed did not show any activity for the key reaction in cocaine formation. So he used a more classical approach − identifying the cocaine-synthesizing enzyme activity in extracts from coca leaves, purifying the responsible protein, isolating the polypeptide, and − after partial sequencing − cloning the corresponding gene. How plants make cocaine Enlarge This is the molecular structure of cocaine (grey: carbon, blue: nitrogen, red: oxygen, white: hydrogen). Credit: Max Planck Institute for Chemical Ecology/ D’Auria Cocaine in young leaves, atropine in roots "We obtained two very interesting results," says Jonathan Gershenzon, director at the institute. "The enzyme reaction analogous to that in atropine synthesis − the conversion of the keto group into an alcohol residue − is catalyzed by a completely different enzyme in coca plants as compared to that in the Solanaceae, namely by an aldo-keto reductase (AKR)." The enzyme was named methylecgonone reductase (MecgoR). AKR enzymes are known in plants and also mammals, amphibians, yeast, protozoa, and bacteria. They are involved in the formation of steroid hormones, for example. The second result is that the MecgoR gene, as well as the protein, is highly active in the very young leaves of coca plants, but not in the roots. Atropine, on the other hand, is synthesized exclusively in the roots of belladonna, from where it is transported into the green organs of the plant. Based on these results, the Max Planck researchers conclude that the tropane alkaloid pathways in coca and belladonna evolved completely independently. Elucidation of the MecgoR-catalyzed step in cocaine biosynthesis represents a major success, but the researchers are now continuing to investigate other important steps in the cocaine pathway. Also of interest is to learn how cocaine is stored in leaf tissue in such high amounts. This alkaloid can account for up to 10% of the dry weight of the immature coca leaf, a phenomenal amount for the accumulation of any one particular alkaloid.