c-ray
02-22-2007, 02:52 AM
from http://www.sciencedaily.com/releases/2007/02/070211200654.htm
[QUOTE]Source: Carnegie Institution
Date: February 12, 2007
Science Daily
humble1
02-22-2007, 03:18 AM
Here's another good one from the same site:
In a new study published online this week in the open-access journal PLoS Biology, Tessa Burch-Smith, Savithramma Dinesh-Kumar, and colleagues show how one aspect of the plant immune system is defined by the gene-for-gene hypothesis: a plant Resistance (R) gene encodes a protein that specifically recognizes and protects against one pathogen or strain of a pathogen carrying a corresponding Avirulence (Avr) gene.
In tobacco and its relatives, the N resistance protein confers resistance to infection by the Tobacco mosaic virus (TMV). The authors used N, and the TMV Avirulence gene, p50, to investigate the mechanism of gene-for-gene resistance.
Contrary to current models, which propose that recognition of resistance genes occurs solely through their leucine-rich repeat domain, the authors show that association is mediated by a completely different region on N's Toll-interleukin-1 receptor homology domain, which is structurally similar to animal innate immunity molecules. These findings provide novel insights into how R proteins recognize pathogen Avr proteins and should help in long-term efforts to enhance crop yield.
Citation: Burch-Smith TM, Schiff M, Caplan JL, Tsao J, Czymmek K, et al. (2007) A novel role for the TIR domain in association with pathogen-derived elicitors. PLoS Biol 5(3): e68. doi:10.1371/journal.pbio.0050068.
Note: This story has been adapted from a news release issued by Public Library of Science
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